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FKBP12 polyclonal antibody



ALX-210-142-R100	100 µl	659.00 USD
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Replaces Prod. #: BML-SA218

Product Details

Alternative Name:	FK506 binding protein (12kDa)

Host:	Rabbit

Immunogen:	Synthetic peptide corresponding to aa 1-13 (G¹VQVETISPGDGR¹³) of human FKBP12 (FK506 binding protein 12kDa).

UniProt ID:	P62942

Species reactivity:	Human, Mouse, Rat

Applications:	IHC (FS), IHC (PS), IP, WB

Recommended Dilutions/Conditions:	Immunohistochemistry (frozen sections, 2µg/ml) Western Blot (1µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Application Notes:	Detects a band of ~12kDa by Western blot.

Purity Detail:	Epitope-affinity purified IgG.

Formulation:	Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.

Handling:	Avoid freeze/thaw cycles.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only

Figure: Western blot of purified FKBP12 after immunoprecipitation on a 15% gel using PAb to FKBP12 (Prod. No. ALX-210-142)."

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Product Literature References

FKBP12-immunopositive inclusions in patients with α-synucleinopathies: Y. Honjo, et al.; Brain Res. 1680, 39 (2018), Application(s): IHC, Abstract;

Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway: C. Chaveroux, et al.; Sci. Rep. 6, 27278 (2016), Application(s): Western blot, Abstract; Full Text

Immunophilin expression in the HIV-infected brain: C.L. Achim, et al.; J. Neuroimmunol. 157, 126 (2004), Abstract;

The effects of FK506 on retinal ganglion cells after optic nerve crush: E.E. Freeman and C.L. Grosskreutz; IOVS 41, 1111 (2000), Abstract;