Replaces Prod. #: BML-SA218
Product Details
Alternative Name: | FK506 binding protein (12kDa) |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to aa 1-13 (G1VQVETISPGDGR13) of human FKBP12 (FK506 binding protein 12kDa). |
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UniProt ID: | P62942 |
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Species reactivity: | Human, Mouse, Rat
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Applications: | IHC (FS), IHC (PS), IP, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (frozen sections, 2µg/ml) Western Blot (1µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~12kDa by Western blot. |
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Purity Detail: | Epitope-affinity purified IgG. |
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Formulation: | Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Western blot of purified FKBP12 after immunoprecipitation on a 15% gel using PAb to FKBP12 (Prod. No.
ALX-210-142)."
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Product Literature References
FKBP12-immunopositive inclusions in patients with α-synucleinopathies: Y. Honjo, et al.; Brain Res.
1680, 39 (2018),
Application(s): IHC,
Abstract;
Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway: C. Chaveroux, et al.; Sci. Rep.
6, 27278 (2016),
Application(s): Western blot,
Abstract;
Full Text
Immunophilin expression in the HIV-infected brain: C.L. Achim, et al.; J. Neuroimmunol.
157, 126 (2004),
Abstract;
The effects of FK506 on retinal ganglion cells after optic nerve crush: E.E. Freeman and C.L. Grosskreutz; IOVS
41, 1111 (2000),
Abstract;