Replaces Prod. #: ALX-210-137/1
Product Details
| Alternative Name: | Glucose regulated protein 78, GRP78 |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to aa 643-654 (T643GEEDTSEKDEL654) of rat BiP (GRP78; glucose regulated protein 78kDa). |
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| UniProt ID: | P06761 |
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| GenBank ID: | M14050 |
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| Species reactivity: | Mouse, Rat
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| Specificity: | Recognizes mouse and rat BiP. Does not detect BiP from human cell lines or COS cells. |
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| Applications: | WB
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| Recommended Dilutions/Conditions: | Western Blot (2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Purity Detail: | Epitope-affinity purified IgG. |
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| Formulation: | Lyophilized. Contains 0.05% sodium azide. |
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| Reconstitution: | Reconstitute with PBS. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure: Western blot of BiP on rat liver lysate using PAb to BiP (Prod. No. ALX-210-137).
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General Literature References
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies: B. Luo & A.S. Lee; Oncogene
32, 805 (2013), (Review),
Abstract;
Full Text
The critical role of GRP78 in physiologic and pathologic stress: K.T. Pfaffenbach & A.S. Lee; Curr. Opin. Cell Biol.
23, 150 (2011), (Review),
Abstract;
Full Text
