Product Details
| Alternative Name: | CaM, Phosphodiesterase 3':5'-cyclic nucleotide activator |
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| MW: | ~17kDa (SDS-PAGE) |
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| Source: | Isolated from pig brain. |
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| MI: | 14: 1719 |
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| Concentration: | 1 mg/ml after reconstitution. |
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| Formulation: | Lyophilized from 5% sucrose, pH 7.0-7.4, containing 10mM sodium phosphate. |
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| Purity: | ≥98% (SDS-PAGE) |
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| Specific Activity: | ≥35’000U/mg protein. One unit will stimulate 0.01 unit of 3’:5’-cyclic nucleotide phosphodiesterase in a 3ml reaction volume at pH 7.5 and 30°C, to 50% of the maximum activity of the enzyme when saturated with CaM in the presence of 100µM Ca2+. |
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| Reconstitution: | Reconstitute with distilled water to 1mg/ml. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. Avoid freeze/thaw cycles. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly: T. Niu, et al.; Nat. Commun.
12, 5862 (2021),
Abstract;
Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C: L. Massom, et al.; Biochemistry
29, 671 (1990),
Abstract;
