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ARH3 (human), (recombinant) (His-tag)

ALX-201-292-C010 10 µg 402.00 USD
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Product Details

Alternative Name:ADP-ribosylhydrolase 3, ADPRHL2
Source:Produced in E. coli. Human ARH3 is fused at the C-terminus to a His-tag.
UniProt ID:Q9NX46
Formulation:Liquid. In PBS with 0.2 mg/mL BSA and 20% glycerol.
Purity Detail:Affinity purified
Application Notes:Functional Application: Hydrolysation of poly-ADP-ribosylated proteins
Shipping:Shipped on Dry Ice
Short Term Storage:-20°C
Long Term Storage:-80°C
Handling:Avoid freeze/thaw cycles.
Regulatory Status:RUO - Research Use Only

Product Literature References

Structural and biochemical evidence supporting arh3 human), (recombinant) (His-ribosylation in the bacterium Deinococcus radiodurans: C.C. Cho, et al.; Nat. Commun. 10, 1491 (2019), Abstract;
An HTS-compatible HTRF assay measuring the glycohydrolase activity of human PARG: A.L. Stowell, et al.; Anal. Biochem. 503, 58 (2016), Abstract;
The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation: C. Mueller-Dieckmann, et al.; PNAS 103, 15026 (2006), Abstract; Full Text

General Literature References

Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix: M. Niere, et al.; Mol. Cell. Biol. 28, 814 (2008), Abstract; Full Text
Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases: F. Koch-Nolte, et al.; Front. Biosc. 13, 6716 (2008), Abstract;
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), Abstract; Full Text

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ALX-201-290-C010 10 µg 402.00 USD
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