Product Specification
| Alternative Name: | NEDD8-specific protease 1, SENP8, Sentrin-specific protease 8, Deneddylase 1 |
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| Source: | Produced in E. coli. |
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| UniProt ID: | Q96LD8 |
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| Concentration: | 1mg/ml |
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| Formulation: | Liquid. In 50mM TRIS-HCl, pH 7.5, 100mM sodium azide, 5mM β-mercaptoethanol and 10% glycerol. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | NEDP1 is a highly conserved cysteine protease that deNEDDylates cullins. NEDP1 appears to be specific for NEDD8 as neither ubiquitin nor SUMO C-terminal extensions are utilized as substrates. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins: H.M. Mendozy, et al.; J. Biol. Chem.
278, 25637 (2003),
Abstract;
