Product Details
| Alternative Name: | Poly(ADP-ribose) polymerase 3 |
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| Source: | Produced in Sf9 insect cells. Produced in a baculovirus expression system. |
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| EC: | 2.4.2.30 |
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| UniProt ID: | Q9Y6F1 |
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| Concentration: | 0.38mg/ml |
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| Formulation: | Liquid. In 50mM TRIS-HCl, pH 7.5, containing 0.25mM EDTA, 7mM β-mercaptoethanol, 0.25mM PMSF and 10% glycerol. |
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| Purity: | ≥97% |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. |
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| Regulatory Status: | RUO - Research Use Only |
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Figure: SDS-PAGE (Coomassie staining) of PARP-3 (human) (rec.) (high purity) (Prod. No.
ALX-201-170)."
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Product Literature References
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function: P. Chang et al.; Nature Cell Biology
7, 1133 (2005),
Abstract;
PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression: A. Augustin, et al.; J. Cell Sci.
116, 1551 (2003),
Abstract;
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