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Prothymosin α (human) (1-99), (recombinant)

ALX-201-125-C050 50 µg 173.00 USD
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Product Specification

Alternative Name:ProTα
Source:Produced in E. coli. Corresponding to the caspase-3 cleavage product of prothymosin α (ProTα) isolated from apoptotic human cells (no affinity-tags, no added additional (linker) sequences). Purified from overproducing bacterial strains by a phenol extraction procedure, DEAE chromatography, and ethanol precipitation.
UniProt ID:P06454
Formulation:Liquid. 50µg dissolved in sterile water.
Shipping:Shipped on Dry Ice
Long Term Storage:-20°C
Technical Info/Product Notes:The exact length of the human protein is 109 aa corresponding to the NCBl data base entries AAH34921 and TNHUA. The N-terminal M is absent in the mature protein (otherwise, it would be 110). ProTα is acetylated at the N-terminal S. MALDI-MS data for the recombinant ProTα isolated from bacteria show that the protein is partially acetylated.
Regulatory Status:RUO - Research Use Only

Product Literature References

Apoptosis-related fragmentation, translocation, and properties of human prothymosin alpha: A.G. Evstafieva, et al.; Exp. Cell Res. 284, 209 (2003), Abstract;
Cytochrome c is transformed from anti- to pro-oxidant when interacting with truncated oncoprotein prothymosin alpha: O.V. Markova, et al.; Biochim. Biophys. Acta 1557, 109 (2003), Abstract;
Sensing prothymosin alpha origin, mutations and conformation with monoclonal antibodies: E.A. Sukhacheva, et al.; J. Immunol. Methods 266, 185 (2002), Abstract;
Overproduction in Escherichia coli, purification and properties of human prothymosin alpha: A.G. Evstafieva, et al.; Eur. J. Biochem. 231, 639 (1995), Abstract;

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