Inhibitor of Src and EGF receptor tyrosine kinases. The peptide sequence corresponds to residues 137-157 of the noncatalytic domain of the transforming protein of Rous sarcoma virus (pp60v-src).
Product Details
| Alternative Name: | Peptide A |
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| Sequence: | H-Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu-OH |
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| Formula: | C111H168N30O35 |
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| MW: | 2482.7 |
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| Purity: | ≥98% |
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| Appearance: | White lyophilized powder. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Evidence for autoinhibitory regulation of the c-src gene product. A possible interaction between the src homology 2 domain and autophosphorylation site: Y. Fukami, et al.; J. Biol. Chem.
268, 1132 (1993),
Abstract;
Full Text
A synthetic peptide corresponding to residues 137 to 157 of p60v-src inhibits tyrosine-specific protein kinases: K. Sato, et al.; BBRC
171, 1152 (1990),
Abstract;
