Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

NBD peptide / NF-κB blocker (cell permeable)

ALX-163-011-1 1 Vial 361.00 USD
Do you need bulk/larger quantities?
For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter.

Product Details

Alternative Name:NEMO-binding domain peptide
Formulation:Liquid. In sterile PBS.
Purity:≥95% (HPLC)
Shipping:Dry Ice
Short Term Storage:-20°C
Long Term Storage:-80°C
Handling:Keep on ice at all times. Protect from moisture. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Regulatory Status:RUO - Research Use Only

Product Literature References

CD163+ macrophages restrain vascular calcification, promoting the development of high-risk plaque: A. Sakamoto, et al.; JCI Insight 8, e154922 (2023), Abstract;
Targeting of NF-κB to Dendritic Spines Is Required for Synaptic Signaling and Spine Development: E.C. Dresselhaus, et al.; J. Neurosci. 38, 4093 (2018), Abstract; Full Text
CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury: H. Akahori, et al.; Nat. Commun. 6, 7792 (2015), Application(s): Intraperitoneal administration in mice, Abstract;
Disruption of IKK-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to HDAC inhibitors: Y. Dai, et al.; J. Biol. Chem. 286, 34036 (2011), Abstract;
Improvement of cardiac contractile function by peptide-based inhibition of NF-kappaB in the utrophin/dystrophin-deficient murine model of muscular dystrophy: D.A. Delfin, et al.; J. Transl. Med. 9, 68 (2011), Abstract; Full Text
Selective inhibition of NF-kappaB blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo: E. Jimi, et al.; Nature Med. 10, 617 (2004), Abstract;
Characterization of the Ikappa B-kinase NEMO binding domain: M.J. May, et al.; J. Biol. Chem. 277, 45992 (2002), Abstract;
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex: M.J. May, et al.; Science 289, 1550 (2000), Abstract;

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
NF-kappaB Inhibitor
By catalog section:


Technical Service
Customer Service