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ORL1 receptor agonist
ALX-163-001-P005 5 mg* 457.00 USD
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ORL1 receptor agonist. The ORL1 receptor structurally resembles opioid receptors and is negatively coupled with adenylyl cyclase.

Product Details

Alternative Name:Orphanin FQ
Quantity:*Sold as net peptide weight
Solubility:Soluble in water.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Inhibitory Effects of a Novel μ-Opioid Receptor Nonpeptide Antagonist, UD-030, on Morphine-Induced Conditioned Place Preference: S. Ide, et al.; Int. J. Mol. Sci. 24, 3551 (2023), Abstract;
Convergent selective signaling impairment exposes the pathogenicity of latrophilin-3 missense variants linked to inheritable ADHD susceptibility: A.L.M. Salinas, et al.; Mol. Psychiatry 27, 2425 (2022), Abstract;
Primary structure and tissue distribution of the orphanin FQ precursor: H.-P. Nothacker, et al.; PNAS 93, 8677 (1996), Abstract;
Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide: Y. Shimohigashi, et al.; J. Biol. Chem. 271, 23642 (1996), Abstract; Full Text
Structure-activity relationship studies on the novel neuropeptide orphanin FQ: R.K. Reinscheid, et al.; J. Biol. Chem. 271, 14163 (1996), Abstract; Full Text
Isolation and structure of the endogenous agonist of opioid receptor- like ORL1 receptor: J.-C. Meunier, et al.; Nature 377, 532 (1995), Abstract;
N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin: Y. Saito, et al.; BBRC 217, 539 (1995), Abstract;
Orphanin FQ: a neuropeptide that activates an opioidlike G protein- coupled receptor: R.K. Reinscheid, et al.; Science 270, 792 (1995), Abstract;

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