Programmed cell death (PCD) in E. coli depends on cell-to-cell communication, a process known as quorum sensing. The communicating cells produce and emit the extracellular death factor (EDF). After reaching a sufficent concentration, EDF activates the cell death pathway in a subset of cells.
Product Details
| Alternative Name: | EDF |
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| Sequence: | H-Asn-Asn-Trp-Asn-Asn-OH |
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| Formula: | C27H36N10O10 |
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| MW: | 660.6 |
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| Source: | Synthetic. |
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| Formulation: | Lyophilized. |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in water or DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli: I. Kolodkin-Gal, et al.; Science
318, 652 (2007),
Abstract;
