Potent, cell permeable and possibly selective inhibitor of protein kinase C (PKC). This product is the N-terminal myristoylated form of Prod. No. ALX-155-021.
Product Details
| Alternative Name: | Epidermal growth factor receptor (651-658) (myristoylated), EGFR (651-658) (myristoylated), HER-1 (651-658) (myristoylated) |
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| Sequence: | Myr-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH |
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| Formula: | C60H117N21O11 |
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| MW: | 1308.7 |
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| Purity: | ≥97% |
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| Appearance: | White lyophilized powder. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibition of protein kinase C by N-myristoylated peptide substrate analogs: N.G. Ward & C.A. O'Brian; Biochemistry
32, 11903 (1993),
Abstract;
Cyanobacteria secondary metabolites-the cyanotoxins: W.W. Carmichael; J. Appl. Bacteriol.
72, 445 (1992),
Abstract;
A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin: C.A. O'Brian, et al.; Invest. New Drugs
9, 169 (1991),
Abstract;
