Highly potent and selective ETB-receptor antagonist.
Product Details
| Alternative Name: | BQ-788 . Na |
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| Sequence: | N-cis-2,6-Dimethylpiperidinocarbonyl-L-γMeLeu-D-Trp(COOMe)-D-Nle-ONa |
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| Formula: | C34H50N5O7Na |
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| MW: | 663.7 |
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| CAS: | 156161-89-6 |
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| Formulation: | Lyophilized from 0.1M sodium bicarbonate. |
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| Peptide Content: | 75-95% |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in methanol (0.5mg/ml), DMSO (4mg/ml), 0.1M sodium bicarbonate (3mg/ml) or 100% ethanol (4mg/ml); insoluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788: K. Ishikawa, et al.; PNAS
91, 4892 (1994),
Abstract;
Clearance of circulating endothelin-1 by ETB receptors in rats: T. Fukuroda, et al.; BBRC
199, 1461 (1994),
Abstract;
