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United States 

ETB receptor antagonist . sodium salt

 
ALX-155-020-MC05 0.5 mg 218.00 USD
 
ALX-155-020-M001 1 mg 279.00 USD
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Highly potent and selective ETB-receptor antagonist.

Product Details

Alternative Name:BQ-788 . Na
 
Sequence:N-cis-2,6-Dimethylpiperidinocarbonyl-L-γMeLeu-D-Trp(COOMe)-D-Nle-ONa
 
Formula:C34H50N5O7Na
 
MW:663.7
 
CAS:156161-89-6
 
Formulation:Lyophilized from 0.1M sodium bicarbonate.
 
Peptide Content:75-95%
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in methanol (0.5mg/ml), DMSO (4mg/ml), 0.1M sodium bicarbonate (3mg/ml) or 100% ethanol (4mg/ml); insoluble in water.
 
Shipping:Ambient Temperature
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
ALX-155-020 structure
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ALX-155-020 structure

Product Literature References

Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788: K. Ishikawa, et al.; PNAS 91, 4892 (1994), Abstract;
Clearance of circulating endothelin-1 by ETB receptors in rats: T. Fukuroda, et al.; BBRC 199, 1461 (1994), Abstract;