Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

ET receptor antagonist [PD 142,893]

ALX-155-008-PC05 0.5 mg* 110.00 USD
ALX-155-008-P001 1 mg* 169.00 USD
Do you need bulk/larger quantities?
Non-selective antagonist of endothelin-1 with high affinity for both the ETA and ETB receptor subtypes.

Product Details

Sequence:Ac-D-Dip-Leu-Asp-Ile-Ile-Trp-OH (D-Dip = D-3,3-Diphenylalanine; Lit. THL 33, 3293 (1992))
Quantity:*Sold as net peptide weight.
Purity:≥97% (HPLC)
Appearance:White lyophilized powder.
Solubility:Soluble in a mixture of 10% acetonitrile and 90% water or in phosphate buffer, pH 7.5.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Endothelin: progress in pharmacology and physiology: W.G. Haynes, et al.; TIPS 14, 225 (1993), (Review), Abstract;
Structure-activity relationships of C-terminal endothelin hexapeptide antagonists: A.M. Doherty, et al.; J. Med. Chem. 36, 2585 (1993), Abstract;
Design of a functional hexapeptide antagonist of endothelin: W.L. Cody, et al.; J. Med. Chem. 35, 3301 (1992), Abstract;