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United States 

Endothelin-1 (human, mouse, rat, pig, bovine, dog)

ALX-155-001-PC01 0.1 mg* 115.00 USD
ALX-155-001-PC05 0.5 mg* 443.00 USD
ALX-155-001-P001 1 mg* 733.00 USD
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Product Details

Alternative Name:ET-1
(Disulfide bonds between Cys1-Cys15and Cys3-Cys11)
MI:14: 3576
Quantity:*Sold as net peptide weight.
Purity:≥98% (HPLC)
Solubility:1mg/ml soluble in DMSO or 5% acetic acid.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Use/Stability:Solution is stable for 1-2 weeks when stored at -20°C. Prepare solution just before use.
Regulatory Status:RUO - Research Use Only

Product Literature References

Inhibition of neurogenic contractions in renal arteries and of cholinergic contractions in coronary arteries by the presumed inhibitor of ADP-ribosylation factor 6, NAV2729: R. Huang, et al.; Naunyn Schmiedebergs Arch. Pharmacol. 395, 471 (2022), Abstract;
Permixon®, hexane-extracted Serenoa repens, inhibits human prostate and bladder smooth muscle contraction and exerts growth-related functions in human prostate stromal cells: A. Tamalunas, et al.; Life Sci. 308, 120931 (2022), Abstract;
Lenalidomide and pomalidomide inhibit growth of prostate stromal cells and human prostate smooth muscle contraction: A. Tamalunas, et al.; Life Sci. 281, 119771 (2021), Abstract;
Endothelin-1 enhanced carotid body chemosensory activity in chronic intermittent hypoxia through PLC, PKC and p38MAPK signaling pathways: J. Li, et al.; Neuropeptides 74, 44 (2019), Abstract;
Interactions of peripheral endothelin-1 and nerve growth factor as contributors to persistent cutaneous pain.: A. Khodorova, et al.; Physiol. Res. 67, S215 (2018), Abstract; Full Text
Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells: J.A. Patel, et al.; Int. J. Mol. Sci. 18, 2372 (2018), Abstract; Full Text
Role of endothelin‑1 and its receptors in cerebral vasospasm following subarachnoid hemorrhage: Y.W. Cheng, et al.; Mol. Med. Rep. 18, 5229 (2018), Abstract;
Mandibular Explant Assay for Investigating Extrinsic Stimuli on Bone and Cartilage Development: J. Jiang, et al.; Bio Protoc. 7, e2641 (2017), Abstract; Full Text
Cloning and sequencing of a bovine preproendothelin cDNA: G.J. Price & L. Malone; Nucleic Acids Res. 18, 3658 (1990), Abstract;
Molecular biology and biochemistry of the endothelins: M. Yanagisawa & T. Masaki; TIPS 10, 374 (1989), Abstract;
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes: A. Inoue, et al.; PNAS 86, 2863 (1989), Abstract;
A novel potent vasoconstrictor peptide produced by vascular endothelial cells [see comments]: M. Yanagisawa, et al.; Nature 332, 411 (1988), Abstract;
Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin: Y. Itoh, et al.; FEBS Lett. 231, 440 (1988), Abstract;
Synthesis and disulfide structure determination of porcine endothelin: an endothelium-derived vasoconstricting peptide: S. Kumagaye, et al.; Int. J. Pept. Prot. Res. 32, 519 (1988), Abstract;