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L-NAME . hydrochloride

NOS inhibitor
ALX-105-003-G005 5 g 93.00 USD
ALX-105-003-G025 25 g 392.00 USD
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Replaces Prod. #: BML-CN242

Inhibitor of nitric oxide synthase (NOS). More soluble than NG-Nitro-L-arginine (Prod. No. ALX-105-001). Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA (Prod. No. ALX-106-001).

Product Details

Alternative Name:NG-Nitro-L-arginine-methyl ester . HCl
Formula:C7H15N5O4 . HCl
MW:233.2 . 36.5
Purity:≥98% (TLC)
Appearance:White to off-white solid.
Solubility:Soluble in water (50mg/ml) or methanol (25g/ml).
Shipping:Ambient Temperature
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Anti-inflammatory Role of Carotenoids in Endothelial Cells Derived from Umbilical Cord of Women Affected by Gestational Diabetes Mellitus: M. Cucci, et al.; Oxid. Med. Cell. Longev. 2019, 8184656 (2019), Abstract; Full Text
Nitric oxide radicals are emitted by wasp eggs to kill mold fung: E. Strohm, et al.; Elife 8, e43718 (2019), Abstract; Full Text
Endothelium- and smooth muscle-dependent vasodilator effects of Citrus aurantium L. var. amara: Focus on Ca2+ modulation: P. Kang, et al. ; Biomed. Pharmacother. 82, 467 (2016), Application(s): Cell culture, Abstract;
Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo: K. Ashina, et al.; PLoS One 10, e0132367 (2015), Application(s): Cell Culture, Abstract; Full Text
Generation of superoxide by purified brain nitric oxide synthase: S. Pou, et al.; J. Biol. Chem. 267, 24173 (1992), Abstract; Full Text
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo: D.D. Rees, et al.; Br. J. Pharmacol. 101, 746 (1990), Abstract;
L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro: P.K. Moore, et al.; Br. J. Pharmacol. 99, 408 (1990), Abstract;

Related Products

L-NMMA . monoacetate 

NOS inhibitor
53308-83-1, ≥99% (TLC) | Print as PDF
ALX-106-001-M025 25 mg 77.00 USD
ALX-106-001-M100 100 mg 270.00 USD
ALX-106-001-G001 1 g 433.00 USD
Do you need bulk/larger quantities?

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