Replaces Prod. #: BML-CN242
Inhibitor of nitric oxide synthase (NOS). More soluble than NG-Nitro-L-arginine (Prod. No. ALX-105-001). Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA (Prod. No. ALX-106-001).
Product Details
| Alternative Name: | NG-Nitro-L-arginine-methyl ester . HCl |
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| Formula: | C7H15N5O4 . HCl |
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| MW: | 233.2 . 36.5 |
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| CAS: | 51298-62-5 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water (50mg/ml) or methanol (25g/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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Nitric oxide radicals are emitted by wasp eggs to kill mold fung: E. Strohm, et al.; Elife
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Abstract;
Full Text
Endothelium- and smooth muscle-dependent vasodilator effects of Citrus aurantium L. var. amara: Focus on Ca2+ modulation: P. Kang, et al. ; Biomed. Pharmacother.
82, 467 (2016),
Application(s): Cell culture,
Abstract;
Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo: K. Ashina, et al.; PLoS One
10, e0132367 (2015),
Application(s): Cell Culture,
Abstract;
Full Text
Generation of superoxide by purified brain nitric oxide synthase: S. Pou, et al.; J. Biol. Chem.
267, 24173 (1992),
Abstract;
Full Text
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo: D.D. Rees, et al.; Br. J. Pharmacol.
101, 746 (1990),
Abstract;
L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro: P.K. Moore, et al.; Br. J. Pharmacol.
99, 408 (1990),
Abstract;
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