Product Details
| Alternative Name: | H-L-Arg-OH |
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| Formula: | C6H14N4O2 |
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| MW: | 174.2 |
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| CAS: | 74-79-3 |
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| MI: | 14: 780 |
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| RTECS: | CF1934200 |
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| Purity: | ≥98% (Titration) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Scientific Background: | Physiological precursor for the formation of nitric oxide (NO) by nitric oxide synthase (NOS). Enhances the release of NO. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The renal transport protein OATP4C1 mediates uptake of the uremic toxin asymmetric dimethylarginine (ADMA) and efflux of cardioprotective L-homoarginine: E. Taghikhani, et al.; PLoS One
14, e0213150 (2019),
Abstract;
Full Text
L-arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide: P. Tsai, et al.; Biochem. Pharmacol.
69, 971 (2005),
Abstract;
Protective effects of L-arginine against cisplatin-induced renal oxidative stress and toxicity: role of nitric oxide: S. Saleh & E. El-Demerdash; Basic Clin. Pharmacol. Toxicol.
97, 91 (2005),
Abstract;
Pharmacokinetics and pharmacodynamics of L-arginine in rats: a model of stimulated neuronal nitric oxide synthesis: E.L. Heinzen & G.M. Pollack; Brain Res.
989, 67 (2003),
Abstract;
L-Arginine supplementation enhances diabetic wound healing: involvement of the nitric oxide synthase and arginase pathways: M.B. Witte, et al.; Metabolism
51, 1269 (2002),
Abstract;
L-arginine increases UVA cytotoxicity in irradiated human keratinocyte cell line: potential role of nitric oxide: C. Didier, et al.; FASEB J.
13, 1817 (1999),
Abstract;
Full Text
The importance of L-arginine metabolism in melanoma: an hypothesis for the role of nitric oxide and polyamines in tumor angiogenesis: M. Joshi; Free Radic. Biol. Med.
22, 573 (1997), (Review),
Abstract;
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides: H.H.H.W. Schmidt, et al.; Science
255, 721 (1992),
Abstract;
L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation: R.M.J. Palmer, et al.; BBRC
153, 1251 (1988),
Abstract;
Vascular endothelial cells synthesize nitric oxide from L-arginine: R.M.J. Palmer, et al.; Nature
333, 664 (1988),
Abstract;
