Product Details
Alternative Name: | Cysteine String Protein, DnaJC5 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of rat CSP. The sequence is completely conserved in bovine. |
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UniProt ID: | P60905 |
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GenBank ID: | U39320 |
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Source: | Purified from rabbit serum. |
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Species reactivity: | Mouse, Rat Bovine, Xenopus
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Applications: | IHC, IP, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry, Immunoprecipitation (0.5µg/ml) Western Blot (1:2,000, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~34kDa by Western blot. |
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Purity Detail: | Immunoaffinity purified. |
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Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Cysteine string protein (CSP) is a 34 kDa rat brain protein localized to the cytoplasmic surface of the synaptic vesicle. CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. |
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Regulatory Status: | RUO - Research Use Only |
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Immunohistochemistry analysis of Xenopus embryonic retina section stained with CSP, pAb.
Western blot analysis of mouse brain tissue extract, probed with CSP, pAb.
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Product Literature References
Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss: B.A. Benitez, et al.; Acta Neuropathol. Commun.
3, 73 (2015),
Application(s): Immunoblotting with human cell lysates,
Abstract;
Full Text
CRHSP-28 regulates Ca(2+)-stimulated secretion in permeabilized acinar cells: G.E. Groblewski, et al. ; J. Biol. Chem.
276, 28866 (2001),
Application(s): WB using rat samples,
Abstract;
Cysteine string protein, a DnaJ family member, is present on diverse secretory vesicles: R.H. Scheller, et al. ; Neuropharmacology
34, 1361 (1995),
Application(s): WB using rat samples,
Abstract;
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