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UGGT polyclonal antibody

ADI-VAP-PT068-E 100 µl 282.00 USD
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Product Specification

Immunogen:Synthetic peptide corresponding to a portion of rat UGGT.
UniProt ID:Q9JLA3
Source:Whole rabbit serum.
Species reactivity:Mouse, Rat
Recommended Dilutions/Conditions:Western Blot (1:100 colorimetric, 1:500 ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~170kDa by Western blot.
Formulation:Liquid. Whole rabbit serum.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides. UGGT catalyzes the transfer of glucose from UDP-glucose to Man7-9GlcNAc2-moiety of unfolded glycoproteins in a Ca2+ dependent reaction. UGGT binds unfolded glycoprotein via an N-acetylglucosamine unit on the oligosaccharide, and hydrophobic amino acids that are exposed in the denatured conformation.
Regulatory Status:RUO - Research Use Only
UGGT polyclonal antibody Western blot
Western blot analysis of rat brain tissue extract, probed with UGGT, pAb.
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UGGT polyclonal antibody Western blot

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