| ADI-VAM-SV041-E | 100 µg | 315.00 USD |  |
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| Alternative Name: | DNM, DYN |
| Clone: | D5 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Recombinant His6-tagged human dynamin. |
| UniProt ID: | Q05193 (Dynamin-1), P50570 (Dynamin-2), Q9UQ16 (Dynamin-3) |
| Source: | Purified from ascites. |
| Species reactivity: | Human, Mouse, Rat Bovine, Chicken |
| Applications: | Flow Cytometry, IHC, IP, WB |
| Recommended Dilutions/Conditions: | Flow Cytometry (10µg/ml) Immunohistochemistry (1:50, human colon cancer tissue) Western Blot (0.5µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~100kDa by Western blot. |
| Purity Detail: | Protein G affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 0.1mM PMSF and 50% glycerol. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Dynamin is a 100 kDa GTP binding protein that was first identified as a protein able to bind microtubules. To date, three genes have been found to encode Dynamin isoforms. Dynamin 1 is neuronal specific, Dynamin 2 is ubiquitously expressed and Dynamin 3 localizes to testis, brain and lung. Dynamin may mediate vesicle formation by assembling into a ring structure around the necks of invaginated coated pits that may eventually lead to the closure of the neck and formation of vesicles. |
| Regulatory Status: | RUO - Research Use Only |
Brain (mouse), (tissue extract) |
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| Mouse brain extract., WB | Print as PDF | ||||||
| ADI-LYT-MB100-F | 200 µg | 117.00 USD | |
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Goat anti-mouse IgG, polyclonal antibody (AP conjugate) |
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| ELISA, WB | Print as PDF | ||||||
| ADI-SAB-101-J | 1 ml | 140.00 USD | |
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Brain (rat), (tissue extract) |
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| Rat brain extract, WB | Print as PDF | ||||||
| ADI-LYT-RB100-F | 200 µg | 117.00 USD | |
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