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Syntaxin monoclonal antibody (SP6)

ADI-VAM-SV013-D 50 µg 170.00 USD
ADI-VAM-SV013-F 200 µg 409.00 USD
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Product Specification

Alternative Name:STX
Immunogen:Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates using anti-human Synaptophysin mAb antibodies.
UniProt ID:Q16623 (syntaxin 1A)
GenBank ID:L37792 (syntaxin 1A)
Source:Purified from ascites.
Species reactivity:Mouse, Rat
Applications:ICC, WB
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~38kDa by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.
Regulatory Status:RUO - Research Use Only
Syntaxin monoclonal antibody (SP6) Western blot
Western blot analysis: Lane 1: MW marker, Lane 2: 20µg Mouse Brain Tissue Extract (ADI-LYT-MB100), Lane 3: 14µg Rat Brain Tissue Extract (Prod. No. ADI-LYT-RB100) probed with Syntaxin mAb (SP6) at 1μg/mL.
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Syntaxin monoclonal antibody (SP6) Western blot

Product Literature References

Assembly of proteins to postsynaptic densities after transient cerebral ischemia: J.A. Zivin, et al. ; J. Neurosci. 18, 625 (1998), Application(s): WB using rat samples, Abstract;
Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex: P. Davies, et al. ; Brain Res. 609, 20 (1993), Application(s): WB, ICC using rat samples, Abstract;

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