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GS28 monoclonal antibody (HFD9)

 
ADI-VAM-PT047-D 50 µg 340.00 USD
 
ADI-VAM-PT047-F 200 µg 590.00 USD
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Product Details

Alternative Name:GOSR1, Golgi SNAP receptor complex member 1
 
Clone:HFD9
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Rat liver Golgi-enriched membranes.
 
UniProt ID:Q62931
 
Source:Purified from ascites.
 
Species reactivity:Mouse, Rat
Bovine, Chicken, Dog, Hamster, Porcine, Rabbit, Sheep
 
Applications:WB
Electron microscopy
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~28kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Golgi SNARE of 28 kDa (GS28), also known as p28 or GOS28, is a 28 kDa integral membrane protein on the surface of the Golgi apparatus that serves as a t-SNARE in ER to Golgi transport. The amino-terminal of GS28 is exposed to the cytosol and is anchored to the cis Golgi via a 20 amino acid carboxyl-terminal hydrophobic tail. GS28 co-immunoprecipitates complexes consisting of Syntaxin 5, Rbet1, Membrin, Rsec22, and Rsly1, and is therefore implicated in ER to-Golgi or intra-Golgi vesicle transport.
 
Regulatory Status:RUO - Research Use Only
 
GS28 monoclonal antibody (HFD9) Western blot
Western blot analysis of pig kidney ESK-4 cell lysate, probed with GS28 mAb (HFD9).
Please mouse over
GS28 monoclonal antibody (HFD9) Western blot

Product Literature References

Data supporting ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion: K. Suga, et al.; Data Brief 5, 782 (2015), Application(s): Western blot, Abstract;
ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion: K. Suga, et al.; Exp. Cell Res. 332, 11 (2015), Application(s): Western Blotting, Abstract;
Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER: D. Yabe, et al. ; PNAS 99, 11694 (2002), Application(s): EM using human samples, Abstract;

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