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Synaptotagmin monoclonal antibody (ASV30)

ADI-SYA-130-D 50 µg 243.00 USD
ADI-SYA-130-F 200 µg 528.00 USD
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Product Details

Alternative Name:SYT
Immunogen:Rat brain synaptic junction protein complexes .
UniProt ID:P21707
GenBank ID:X52772
Source:Purified from mouse ascites.
Species reactivity:Human, Mouse, Rat
Applications:IHC, WB
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~65kDa by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:Synaptotagmins (Syt) are membrane-trafficking proteins characterized by an N-terminal transmembrane region, a variable linker, and two C-terminal C2-domains, C2A and C2B. At least twelve Synaptotagamins are expressed in vertebrates and can be found in both vesicular and plasma membranes.
Regulatory Status:RUO - Research Use Only
Synaptotagmin monoclonal antibody (ASV30) Western blot
Western blot analysis of Synaptotagmin: Lane 1: MW marker, Lane 2: Mouse Brain Tissue Lysate (Prod No. ADI-LYT-MB100), Lane 3: Rat Brain Tissue Lysate (Prod No. ADI-LYT-RB100).
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Synaptotagmin monoclonal antibody (ASV30) Western blot

Product Literature References

An ultra-stable cytoplasmic antibody engineered for in vivo applications: H. Kabayama, et al.; Nat. Commun. 11, 336 (2020), Abstract; Full Text
Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I: C.L. Schengrund, et al. ; J. Biol. Chem. 277, 32815 (2002), Application(s): WB using human & mouse samples, Abstract;
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecterory tissue: W.D. Matthew, et al.; J. Cell Biol. 91, 257 (1981), Application(s): WB, IHC using rat samples, Abstract;

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