| ADI-SPA-541-E | 100 µg | 296.00 USD |  |
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| Alternative Name: | GPX1, GPX |
| Clone: | GPX-347 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Native human glutathione peroxidase. |
| Species reactivity: | Human |
| Specificity: | Recognizes human GPX1. |
| Applications: | ICC, WB |
| Recommended Dilutions/Conditions: | Immunocytochemistry (1-10µg/ml) Western Blot (10µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~23kDa by Western blot. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Liquid. In PBS containing 50% glycerol. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease. |
| Regulatory Status: | RUO - Research Use Only |
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