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Cpn10 polyclonal antibody

ADI-SPA-110-D 50 µg 174.00 USD
ADI-SPA-110-F 200 µg 444.00 USD
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Product Details

Alternative Name:HSP10, HSPE1, GroES, Heat shock protein 10, Chaperonin 10
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human Cpn10.
UniProt ID:P61604
Gene/Protein Identifier:NM_002157 (RefSeq)
Source:Purified from rabbit serum.
Species reactivity:Human, Mouse, Rat
Bovine, Dog, Guinea pig, Porcine, Rabbit, Sheep, Xenopus
Applications:IHC (PS), WB
Recommended Dilutions/Conditions:Western Blot (1:2,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~10kDa by Western blot.
Purity Detail:Protein A affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:Chaperonin 10 (Cpn10 or Hsp10), is the ~10 kDa mammalian equivalent to GroES of E. coli. Chaperonins play fundamental roles in the folding, assembly, and translocation of other proteins. Chaperonin 10 has been located in human platelets but more importantly it may also be present in human maternal serum. It has been reported that human Cpn10 is identical with Early pregnancy factor (EPF), which is involved in control over cell growth and development.
Technical Info/Product Notes:Recommended by the Human Protein Atlas Organization for IHC (Ensembl No. ENSG00000115541).
Regulatory Status:RUO - Research Use Only
Cpn10 polyclonal antibody Immunohistochemistry
IHC Analysis: Human colon tissue stained with Cpn10, pAb at 10µg/ml.
Cpn10 polyclonal antibody Western blot
Western blot analysis of human HeLa (heat shocked) cell lysate, probed with Cpn10 (Hsp10) pAb.
Cpn10 polyclonal antibody Immunohistochemistry
IHC Analysis: Human testis tissue stained with Cpn10, pAb at 10µg/ml.
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Cpn10 polyclonal antibody Immunohistochemistry Cpn10 polyclonal antibody Western blot Cpn10 polyclonal antibody Immunohistochemistry

Product Literature References

Impairment of mitochondrial unfolded protein response contribute to resistance declination of H2 O2 -induced injury in senescent MRC-5 cell model: T.Y. Lee, et al.; Kaohsiung J. Med. Sci. 36, 89 (2020), Abstract; Full Text
Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone: S. Corvera, et al. ; Mol. Cell. Biol. 23, 1085 (2003), Application(s): WB using mouse samples, Abstract;
Overexpression of heat shock protein 60/10 in myocardium of patients with chronic atrial fibrillation: B. Schumacher, et al. ; Ann. Thorac. Surg. 74, 767 (2002), Application(s): WB using human samples, Abstract;
Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells: S. Orrenius, et al. ; EMBO J. 18, 2040 (1999), Application(s): WB using human samples, Abstract;

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HSP10 Polyclonal antibody
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