| Alternative Name: | Serum-glucocorticoid regulated kinase |
| |
| MW: | ~73kDa |
| |
| Source: | Active recombinant human SGK-1 (truncated NT 60 aa) produced in Sf9 insect cells using an N-terminal GST-tag. Produced in a baculovirus expression system. |
| |
| UniProt ID: | O00141 |
| |
| Formulation: | Liquid. In 50mM TRIS-HCl, pH 7.5, containing 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, and 25% glycerol. |
| |
| Purity: | ≥90% (SDS-PAGE) |
| |
| Purity Detail: | Purified by multi-step chromatography. |
| |
| Applications: | Kinase assay
|
| |
| Shipping: | Shipped on Dry Ice |
| |
| Long Term Storage: | -80°C |
| |
| Scientific Background: | SGKs (Serum and glucocorticoid-inducible kinases) are serine/threonine kinases belonging to the AGC subfamily. There are 3 isoforms, SGK1, SGK2, and SGK3. SGK1 plays an important role in activating certain potassium, sodium and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
