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Biliverdin Reductase polyclonal antibody

 
ADI-OSA-450-E 100 µl 414.00 USD
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Product Details

Alternative Name:BLVR
 
Host:Rabbit
 
Immunogen:Recombinant rat Biliverdin Reductase.
 
UniProt ID:P46844
 
GenBank ID:M81681
 
Source:Purified from rabbit serum.
 
Species reactivity:Mouse, Rat
E. coli
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (1:100)
Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects bands of ~33kDa by Western blot.
 
Purity Detail:Ammonium sulfate precipitation purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The phosphoprotein BVR (Biliverdin Reductase) is an oxireductase which catalyzes the reduction of the gamma-meso bridge of Biliverdin to Bilirubin. BVR is unique among all enzymes characterized to date because BVR has dual pH/dual cofactor requirements. The reductase is highly conserved in its primary structure and molecular properties and uses NADH in the acidic range (peak activity at pH~6.7), whereas NADPH is utilized in the basic range (peak activity at pH ~8.7).
 
Regulatory Status:RUO - Research Use Only
 
Biliverdin Reductase polyclonal antibody Western blot
Western blot analysis of Biliverdin Reductase, pAb (Prod. No. ADI-OSA-450): Lane 1: MW Marker, Lane 2: Biliverdin Reductase Protein (rat) (recombinant) (Prod. No. ADI-OSP-450), Lane 3: Rat-2 Cell Lysate, Lane 4: 3T3 Cell Lysate (Prod. No. ADI-LYC-3T100), Lane 5: PC-12 Cell Lysate (Prod. No. ADI-LYC-PC100), Lane 6: HO-1 Protein (rat) (recombinant) (Prod. No. ADI-SPP-730)
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Biliverdin Reductase polyclonal antibody Western blot

Product Literature References

Induction of BVR-A Expression by Korean Red Ginseng in Murine Hippocampal Astrocytes: Role of Bilirubin in Mitochondrial Function via the LKB1-SIRT1-ERRα Axis: S. Moon, et al.; Antioxidants 11, 1742 (2022), Abstract;

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