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GST-π polyclonal antibody

ADI-MSA-102-E 100 µl 328.00 USD
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Product Details

Alternative Name:GST-P, Glutathione S-transferase P, GSTP1
Immunogen:Human placental GST-π.
UniProt ID:P09211
Species reactivity:Human, Mouse, Rat
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (1:500-1:1,000)
Western Blot (1:500-1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~26kDa by Western blot.
Purity Detail:Protein A affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:The GST superfamily of enzymes play an important role in detoxification of xenobiotics by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. There are four main GST classes; alpha, mu, pi, and tau. GST-P is a member of the pi class of GSTs, and its expression is specifically increased in the early stages of rat hepatocarcinogenesis. Due to its high affinity for glutathione, GST is frequently utilized as an approximately 26 kDa fusion tag for the expression and purification of recombinant proteins.
Regulatory Status:RUO - Research Use Only
GST-π polyclonal antibody Western blot
Western blot analysis of mouse liver tissue extract, probed with GST-p pAb.
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GST-π polyclonal antibody Western blot

Product Literature References

Heat shock protein amplification improves cerebellar myelination in the Npc1nih mouse model: J. Gray, et al.; EBioMedicine 86, 104374 (2022), Abstract;
Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence: A. Manousi, et al.; EBioMedicine 65, 103276 (2021), Abstract; Full Text
Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice-a behavioral and immunohistochemical study: I. Kostadinova, et al.; Amino Acids 53, 1279 (2021), Abstract;
Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence: A.C. Carvalho, et al.; Free Radic. Biol. Med. 83, 262 (2015), Application(s): Western Blotting, Abstract;
Combination of growth factors enhances remyelination in acuprizone-induced demyelination mouse model: J. de Vellis, et al. ; Neurochem. Res. 32, 783 (2007), Application(s): IHC using mouse tissue, Abstract;

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