| ADI-KAP-TF132-E | 100 µg | 479.00 USD |  |
||
| Do you need bulk/larger quantities? | |||||
| Alternative Name: | IκB kinase, NEMO |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human IKKγ. The sequence is completely conserved in mouse. |
| UniProt ID: | Q9Y6K9 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | ICC, WB |
| Recommended Dilutions/Conditions: | Western Blot (0.5-1.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~52kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Nuclear factor κ B (NF-κB) is a ubiquitous and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-κB activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A molecule in the IKK complex was identified and designated IKKepsilon/IKK-iota. |
| Regulatory Status: | RUO - Research Use Only |
