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IRAK-M polyclonal antibody

ADI-KAP-ST207-E 100 µg 479.00 USD
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Product Details

Alternative Name:interleukin-1 receptor-associated kinase
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human IRAK-M.
UniProt ID:Q9Y616
Species reactivity:Human, Mouse, Rat
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (2µg/ml)
Western Blot (0.5-1.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~68kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression.
Regulatory Status:RUO - Research Use Only
IRAK-M polyclonal antibody Immunohistochemistry
Immunohistochemistry analysis of rat liver cells using IRAK-M antibody at 2µg/ml.
IRAK-M polyclonal antibody Western blot
Western blot analysis of IRAK-M in mouse spleen (M) and rat liver (R) tissue lysates with IRAK-M antibody at 1µg/ml.
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IRAK-M polyclonal antibody Immunohistochemistry IRAK-M polyclonal antibody Western blot

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