Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to a portion of human Caveolin-2. |
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UniProt ID: | P51636 |
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Species reactivity: | Human
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Applications: | WB
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Recommended Dilutions/Conditions: | Western Blot (0.2-1.0µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In buffer containing 50% glycerol, 1.0mg/ml BSA, and 0.01% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Caveolae are specialized plasma membrane associated organelles that participate in numerous cellular functions including endocytosis, potocytosis, transcytosis, signal transduction, and cholesterol trafficking. The major proteins that form caveolae are the caveolins of which there are three major isoforms. Caveolin-2 has been shown to positively regulate Caveolin-1-dependent caveolae biogenesis and this phenomenon is contingent on the phosphorylation of Caveolin-2 on serines 23 and 36. |
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Regulatory Status: | RUO - Research Use Only |
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