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eIF4E-BP2 polyclonal antibody

ADI-KAP-MA112-E 100 µg 328.00 USD
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Product Details

Alternative Name:Eukaryotic translation initiation factor 4E-binding protein 2
Immunogen:Synthetic peptide corresponding to a portion of human eIF4E-BP2. The sequence is completely conserved in mouse.
UniProt ID:Q13542
GenBank ID:L36056
Source:Purified from rabbit serum.
Species reactivity:Human, Mouse, Rat
Bovine, Dog, Porcine, Rabbit
Applications:IHC (PS), WB
Recommended Dilutions/Conditions:Western Blot (4µg/ml colorimetric, 4µg/ml ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In borate buffered saline, pH 8.4, containing 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, and 5mM EDTA.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:The eukaryotic translation initiation factors (eIFs) regulate translation at the level of messenger RNA engagement by the ribosome. eIF-2alpha promotes the binding of the initiator tRNA to 40S ribosomal subunits, and is a key signaling component of the unfolded protein response (UPR). eIF-4E recruits mRNAs to the eIF4F complex through binding of their 5 N7-methylguanosine cap. eIF-4E binding proteins-1 and -2 are translational repressors, sequestering eIF-4E in conditions of low cellular demand for translation. Their dissociation from eIF-4E is regulated by phosphorylation in response to growth-promoting stimuli.
Regulatory Status:RUO - Research Use Only
eIF4E-BP2 polyclonal antibody Western blot
eIF4E-BP2 polyclonal antibody Immunohistochemistry
IHC Analysis: Human pancreas tissue stained with eIF4E-BP2, pAb at 10µg/ml.
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eIF4E-BP2 polyclonal antibody Western blot eIF4E-BP2 polyclonal antibody Immunohistochemistry

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