| ADI-KAP-MA014-C | 25 µg | 120.00 USD |  |
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| ADI-KAP-MA014-E | 100 µg | 295.00 USD | |
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| Alternative Name: | MAP2K6, MAP kinase kinase 6 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human MEK6. |
| UniProt ID: | P52564 |
| GenBank ID: | U39656 |
| Source: | Purified from rabbit serum. |
| Species reactivity: | Human, Mouse, Rat Xenopus |
| Applications: | IHC, IP, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (5µg/ml) Immunoprecipitation (4µg/ml) Western Blot (4µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~38kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In borate buffered saline, pH 8.2, containing 50% glycerol and 0.09% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Members of the MAP kinase family of protein kinases (e.g. p38 and Jnk) are subject to dual phosphorylation of a conserved T-X-Y motif in their activation domain by upstream members of the MAP/ERK kinase (MEK/MKK) family. MKK3 and MKK6 phosphorylate p38 in response to cytokine stimulation and cellular stress, while MKK7 and MKK4 activate the Jnk kinases by phosphorylation of the threonine and tyrosine residues, respectively. |
| Regulatory Status: | RUO - Research Use Only |
