Alternative Name: | KREV1 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to a portion of human Rap1a. The sequence is completely conserved in mouse, rat, bovine, chicken, Xenopus. Differs from a portion of Rap1b by 2 amino acids. |
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UniProt ID: | P62834 (Rap1A), P61224 (Rap1B) |
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GenBank ID: | A08691 |
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Source: | Purified from rabbit serum. |
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Species reactivity: | Human, Mouse, Rat Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus
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Applications: | WB
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Recommended Dilutions/Conditions: | Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~25kDa by Western blot. |
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In PBS. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known. |
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Regulatory Status: | RUO - Research Use Only |
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