| ADI-KAP-CC015-E | 100 µl | 444.00 USD |  |
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| Alternative Name: | Cell division cycle 2, Cyclin-dependent kinase 1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human Cdk1/cdc2 phosphorylated at Tyr15. The sequence is completely conserved in mouse, rat, Drosophila and Xenopus. |
| UniProt ID: | P06493 |
| Species reactivity: | Human, Mouse, Rat Xenopus |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins. |
| Regulatory Status: | RUO - Research Use Only |
![[pTyr15]Cdk1/cdc2 polyclonal antibody Western blot](https://www.enzolifesciences.com/fileadmin/files/image/KAP-CC015-Antibody-Blot.gif "[pTyr15]Cdk1/cdc2 polyclonal antibody Western blot")
![[pTyr15]Cdk1/cdc2 polyclonal antibody Western blot](https://www.enzolifesciences.com/fileadmin/thumbs/7075b569443429c9ed0c89af1e76c19867aed38e-KAP-CC015-Antibody-Blot.gif.jpg "[pTyr15]Cdk1/cdc2 polyclonal antibody Western blot")
