Alternative Name: | Cyclin G-associated kinase |
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Clone: | 1C2 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Recombinant rat GAK. |
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UniProt ID: | P97874 |
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Species reactivity: | Human, Mouse, Rat
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Applications: | WB
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Recommended Dilutions/Conditions: | Western Blot (1µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In PBS containing 50% glycerol. No preservatives. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | GAK, Cyclin G-associated kinase, is a protein that associates with Cyclin G1. The predicted amino acid sequence of GAK shows it has a serine/threonine protein kinase catalytic domain in the N-terminal and a long C-terminal extension that shares homology with tensin and auxilin, and contains a leucine zipper region. GAK is thought to play a role as a modulator of signal transduction by relaying the phosphorylation signal from an unidentified tyrosine kinase to an unidentified GAK phosphorylation target. |
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Regulatory Status: | RUO - Research Use Only |
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