| ADI-KAM-CC239-E | 100 µg | 354.00 USD |  |
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| Alternative Name: | TRP53, Tumor protein p53 |
| Clone: | FPS315 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to a portion of human p53 phosphorylated at Ser315. |
| UniProt ID: | P04637 |
| Species reactivity: | Human |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (5µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Western Blot (5µg/ml, ECL) Optimal conditions must be determined individually for each application. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma. |
| Regulatory Status: | RUO - Research Use Only |
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