| ADI-KAM-CC203-F | 200 µl | 263.00 USD |  |
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| Do you need bulk/larger quantities? | |||||
| Alternative Name: | CCND3 |
| Clone: | DCS-22 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Recombinant human Cyclin D3. |
| UniProt ID: | P30281 |
| Species reactivity: | Human |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (1:20-1:40) Western Blot (1:100-1:200, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Formulation: | Liquid. In concentrated mouse immunoglobulin containing 0.1% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Cyclins are a family of proteins which function as the regulatory subunits of cyclin/cyclin-dependent kinase (Cdk) holoenzymes, mediating entry into and progression through the cell cycle. Each cyclin is expressed in a temporal fashion during the cell cycle, partnering with a specific Cdk to activate its protein kinase activity. The most well defined mitotic cyclins are: cyclin D, which partners with cdks 4 and 6 during early G1 phase; cyclin E, which activates Cdk2 in the G1 to S phase transition; cyclin A, which utilizes Cdks 1 and 2 during progression through S phase and into G2; and cyclin B, which activates Cdk1 in M-phase promotion. |
| Regulatory Status: | RUO - Research Use Only |
