Alternative Name: | Protein kinase C inhibitor protein, Protein 1054 |
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Clone: | 4E1 |
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Host: | Mouse |
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Isotype: | IgG2b |
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Immunogen: | Recombinant rat 14-3-3 β. |
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UniProt ID: | P35213 |
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GenBank ID: | AAA13843 |
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Species reactivity: | Mouse, Rat
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Applications: | IP, WB
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Recommended Dilutions/Conditions: | Immunoprecipitation (5-10µg/ml) Western Blot (1-5µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Lyophilized. In PBS, pH 7.4, containing 10mg/ml sucrose and 1mg/ml sodium azide. For a stock solution of 1.0mg/ml reconstitute with 100μl of sterile distilled water. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | 14-3-3 proteins are highly conserved proteins that play a role in both signal transduction and progression through the cell cycle by binding to and regulating a number of different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms. |
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Regulatory Status: | RUO - Research Use Only |
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