| Alternative Name: | Protein kinase C inhibitor protein, Protein 1054 |
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| Clone: | 3C8 |
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| Host: | Mouse |
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| Isotype: | IgG2b |
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| Immunogen: | Recombinant human 14-3-3 β. |
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| UniProt ID: | P31946 (14-3-3 beta), P62258 (14-3-3 epsilon), P63104 (14-3-3 zeta) |
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| Gene/Protein Identifier: | NP_003395 (RefSeq of 14-3-3 beta), NP_006752 (RefSeq of 14-3-3 epsilon), NP_663723 (RefSeq of 14-3-3 zeta) |
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| Species reactivity: | Human, Mouse, Rat
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| Applications: | WB
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| Recommended Dilutions/Conditions: | Western Blot (1-10µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Purity Detail: | Protein A affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.2, containing 1% sucrose and 0.1% sodium azide. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | 14-3-3 proteins are highly conserved proteins that play a role in both signal transduction and progression through the cell cycle by binding to and regulating a number of different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms. |
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| Regulatory Status: | RUO - Research Use Only |
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