Product Details
| Alternative Name: | Heat shock protein 65 |
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| MW: | ~65kDa |
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| Source: | Produced in E. coli. |
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| UniProt ID: | P0A521 |
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| Formulation: | Liquid. In 1x Dulbecco's PBS. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Purity Detail: | Purified by multi-step chromatography. |
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| Endotoxin Content: | <50EU/mg purified protein (LAL test) |
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| Applications: | WB
Activity assay, Antigen microarray
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| Application Notes: | ATPase activity assay (positive). Western blot control. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | Hsp65, a 65 kDa protein isolated from Mycobacterium bovis BCG, is a member of the hsp60 family of heat shock proteins. Sequence comparison of Hsp65 from different mycobacterium strains showed that the protein sequence of M. bovis BCG is identical to that of M. tuberculosis, and very similar to that of M. leprae, the pathogens that cause tuberculosis and tuberculoid leprosy, respectively. M. bovis BCG Hsp65 was identified as the immunodominant antigen during mycobacterial diseases and vaccination. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis: H. Weiner, et al. ; PNAS
105, 18889 (2008),
Application(s): Antigen Microarray using human serum,
Abstract;
