Alternative Name: | A-Proliferation-inducing ligand, TNFSF 13, CD256 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to a portion of human APRIL. |
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UniProt ID: | O75888 |
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Species reactivity: | Human, Mouse
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Applications: | IHC, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (10µg/ml) Western Blot (1-4µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~27kDa by Western blot. |
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | APRIL (A proliferation-inducing ligand) is a member of the TNF family. APRIL stimulates B- and T-cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL and its close relative BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
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Regulatory Status: | RUO - Research Use Only |
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