Product Details
Alternative Name: | Toll-like receptor 4 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to a portion of mouse TLR4. |
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UniProt ID: | Q9QUK6, Q8K2T5 |
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GenBank ID: | AAH29856 |
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Species reactivity: | Mouse
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Applications: | ICC, IHC (PS), WB
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Recommended Dilutions/Conditions: | Immunocytochemistry (1:10) Immunohistochemistry (1:50, paraffin) Western Blot (1-3µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~90kDa by Western blot. |
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In PBS containing 0.05% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands. |
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Regulatory Status: | RUO - Research Use Only |
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Western blot analysis of recombinant mouse TLR4, protein, probed with TLR4 pAb.
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Product Literature References
Fenofibrate improves high-fat diet-induced and palmitate-induced endoplasmic reticulum stress and inflammation in skeletal muscle: F. Dai, et al.; Life Sci.
157, 158 (2016),
Application(s): Western blot,
Abstract;