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Tapasin polyclonal antibody

ADI-CSA-630-D 50 µg 179.00 USD
ADI-CSA-630-F 200 µg 429.00 USD
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Product Details

Alternative Name:TPN, TPSN, TAP binding protein
Immunogen:Synthetic peptide corresponding to aa 2-20 of human tapasin with a cysteine residue added.
UniProt ID:O15533
GenBank ID:AF009510
Source:Purified from rabbit serum.
Species reactivity:Human
Crossreactivity:Weakly cross-reacts with bovine Tapasin.
Applications:IP, WB
Recommended Dilutions/Conditions:Immunoprecipitation (1:100)
Western Blot (1:1,000, colorimetric and ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~48kDa by Western blot.
Purity Detail:Protein A affinity purified.
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Tapasin is a 48 kDa glycoprotein which is a member of the immunoglobulin superfamily and is required for efficient peptide binding to TAP (Transporter associated with antigen processing). TAP binds peptides in its cytosolic part and subsequently translocates the peptides into the lumen of the endoplasmic reticulum where assembly of MHC class I and peptide takes place.
Regulatory Status:RUO - Research Use Only
Tapasin polyclonal antibody Western blot
Western blot analysis of Tapasin, PAb: Lane 1: MW marker, Lane 2: A431 Lysate (Prod No.: ADI-LYC-4100)
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Tapasin polyclonal antibody Western blot

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