| ADI-CSA-614-E | 100 µg | 386.00 USD |  |
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| Alternative Name: | SBP-1, High-mobility group box 1 |
| Clone: | KS1 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | Pig HMGB1 (HMG1). |
| UniProt ID: | P12682 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (5µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~29kDa by Western blot. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Liquid. In PBS containing 50% glycerol. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The chromatin non-histone high mobility group of proteins (HMG)-1 and -2 contain conserved domains known as HMG-boxes. Both HMG-1 and HMG-2 contain an N-terminal HMG box, a central HMG box and an acidic carboxy terminus. HMG-1/2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites, such as steroid hormone receptors, and p53. |
| Regulatory Status: | RUO - Research Use Only |
