| ADI-CSA-515-E | 100 µg | 357.00 USD |  |
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| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human TIRP. |
| UniProt ID: | Q86XR7 |
| GenBank ID: | AAP81748 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (2µg/ml) Western Blot (0.5-2.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~25kDa by Western blot. |
| Purity Detail: | Ion exchange purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | TIRP is a member of the Toll/Interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κB. |
| Regulatory Status: | RUO - Research Use Only |
