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ST2 polyclonal antibody

ADI-CSA-512-E 100 µg 493.00 USD
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Product Details

Alternative Name:Interleukin-1 receptor-like 1, Lymphocyte antigen 84
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of mouse ST2. The sequence is common to all three ST2 isoforms.
UniProt ID:P14719
GenBank ID:BAA02854
Species reactivity:Human, Mouse
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (2µg/ml)
Western Blot (1-2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~45kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). ST2 was originally identified as a protein whose production was stimulated by various proliferation inducing agents such as PDGF and FGF. Additionally, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance.
Regulatory Status:RUO - Research Use Only
ST2 polyclonal antibody Immunohistochemistry
Immunohistochemistry analysis of ST2 in mouse kidney tissue with ST2 antibody at 2µg/ml.
ST2 polyclonal antibody Western blot
Western blot analysis of ST2 in mouse kidney lysate with ST2 antibody at 1µg/ml in the presence (lane A) or absence (lane B) of 1µg blocking peptide.
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ST2 polyclonal antibody Immunohistochemistry ST2 polyclonal antibody Western blot

Product Literature References

Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats: C. Sitzia, et al.; Int. J. Mol. Sci. 24, 1991 (2023), Abstract;

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