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MyD88 polyclonal antibody

ADI-CSA-510-E 100 µg 494.00 USD
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Product Details

Alternative Name:Myeloid differentiation primary response gene
Immunogen:Synthetic peptide corresponding to a portion of human MyD88. The sequence is completely conserved in mouse.
UniProt ID:Q99836
GenBank ID:NM_002468.1 (RefSeq)
Species reactivity:Human, Mouse, Rat
Recommended Dilutions/Conditions:Western Blot (1-2µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~35kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:MyD88 (Myeloid differentiation primary response gene 88) is a general adapter protein for the Toll/IL-1R family of receptors that have been shown to induce growth arrest, terminal differentiation, and apoptosis. MyD88 plays an important role in the inflammatory response induced by cytokines, IL-1 and IL-18, and endotoxin. It has been shown that signaling via MyD88 is essential for an LPS response. MyD88 is a cytoplasmic protein, which is expressed in many tissues.
Regulatory Status:RUO - Research Use Only
MyD88 polyclonal antibody Western blot
Western blot analysis of MyD88 in Jurkat whole cell lysate with MyD88 antibody at 1:500 dilution.
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MyD88 polyclonal antibody Western blot

Product Literature References

IRAK-M is a negative regulator of Toll-like receptor signaling: R.A. Flavell, et al. ; Cell 110, 191 (2002), Application(s): WB using mouse samples, Abstract;

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