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Agrin monoclonal antibody (Agr-33)

ADI-AGR-510-D 50 µg 253.00 USD
ADI-AGR-510-F 200 µg 501.00 USD
ADI-AGR-510-J 1 mg 2,092.00 USD
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Product Details

Immunogen:Recombinant rat agrin (C-terminal fragment).
UniProt ID:P25304
GenBank ID:M64780
Source:Purified from hybridoma tissue culture supernatant.
Species reactivity:Mouse, Rat
Applications:ICC, IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (10µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation.
Regulatory Status:RUO - Research Use Only
Agrin monoclonal antibody (Agr-33) Immunohistochemistry
Immunohistochemistry analysis of rat skeletal muscle probed with Agrin, mAb (Agr-33) at 1:100.
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Agrin monoclonal antibody (Agr-33) Immunohistochemistry

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