Alternative Name: | Apo-2L, TNFSF 10, CD253 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human TRAIL. |
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UniProt ID: | P50591 |
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GenBank ID: | U57059 |
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Gene/Protein Identifier: | 8743 (Entrez GeneID) |
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Species reactivity: | Human
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Applications: | IHC, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (20µg/ml) Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects bands of ~32kDa and ~24kDa (membrane and soluble forms) by Western blot. |
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Purity Detail: | Ion exchange purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two death domain containing receptors, DR4 and DR5, have been identified as the receptors for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-κB activation in many tissues and cells. |
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Regulatory Status: | RUO - Research Use Only |
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